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Research

Research

Interview with Rami Sommerstein

Prof. Rami Sommerstein, Professor of Infectious Diseases and Public Health Epidemiology, Faculty of Medicine, University of Bern, heads the 'SSI Intervention' module at Swissnoso.

Morbus Hirschsprung
Research

Morbus Hirschsprung

Hirschsprung`s disease is a multigenetic intestinal disorder characterized by a variable length of distal colonic aganglionosis. The exact cause is unknown but proposed pathological mechanisms are processes of the enteric neural crest-derived cell development and include faulty proliferation, insufficient cephocaudal migration, differentiation, and survival [1]. The consequences are continuous contraction and lack of peristalsis leading to functional intestinal obstruction at the terminal migratory site of ganglion cells [2]. Although Hirschsprung`s disease can affect any length from the internal anal sphincter to the entire large bowel the incidence is approximately 1 in 5000 births, with a male predominance of 4:1 in rectosigmoid Hirschsprung`s disease [3].

 

Surgical Research in Switzerland
Research

Surgical Research in Switzerland

Möchten Sie im SWISS/KNIFE auch Ihre Publikationen auflisten? Die Redaktion ist dankbar für Einsendungen und Hinweise. Wenden Sie sich bitte per Mail an: sarah.peisl@unibe.ch.

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